This edition of NCI Investigational Drugs - Chemical Information is designed to provide those involved in various phases of drug development with chemical and physical data on compounds which are past or current development candidates in the Developmental Therapeutics Program, Division of Cancer Treatment Diagnosis and Centers, National Cancer Institute. These range from agents which have only just entered the development pipeline to those which are available commercially. Monographs for the majority of investigational agents currently distributed by the DCTD for clinical study are included.
A uniform format has been followed in presenting the various properties included for compounds listed in this book. It should, however, be borne in mind that several decades will have elapsed from the time data was obtained on early compounds and data acquisition on very recent agents. The amount of information available on the various compounds consequently differ markedly.